https:\/\/chunglab.med.upenn.edu\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Neural circuits underlying sleep and emotional regulation January 10 Noon – 1:00 p.m. PST Where SCCRS 250 and via Zoom Meeting ID: 923 5507 9987 Passcode: 821370 About the speaker […]<\/p>\n","protected":false},"author":26507,"featured_media":25961,"comment_status":"open","ping_status":"closed","template":"","meta":{"_wsuwp_accessibility_report":[],"_tribe_events_status":"","_tribe_events_status_reason":""},"tags":[],"tribe_events_cat":[66],"wsuwp_university_location":[],"wsuwp_university_org":[],"event_city":"Spokane","event_state":"WA","event_venue":"SCCRS 250","event_organizer":"","event_organizer_email":"","event_organizer_phone":"","event_organizer_website":"","event_website":"https:\/\/wsu.zoom.us\/j\/92355079987?pwd=THhob2Z5RWNCdXFoVjgrMTROOCt0dz09&from=addon","event_cost":"","event_excerpt":"Neural circuits underlying sleep and emotional regulation\nJanuary 10\nNoon – 1:00 p.m. PST\nWhere\nSCCRS 250 and via Zoom\nMeeting ID: 923 5507 9987\nPasscode: 821370\nAbout the speaker and seminar:\nShinjae Chung, PhD, Assistant Professor in Department of Neuroscience, Chronobiology Program, Perelman School of Medicine, University of Pennsylvania, will be giving the Translational Medicine and Physiology’s seminar entitled \u201cNeural circuits underlying sleep and emotional regulation”.\nGood quality sleep is essential for our well-being. Sleep disturbances can therefore negatively impact our mental and physical health. We show that acute psychosocial stress in mice disrupts sleep, by causing frequent arousals, disrupting slow (~minute) oscillations in the electroencephalogram and suppressing REMs. These changes were reflected in frequent activation of noradrenergic neurons in the locus coeruleus (LC-NE) during NREMs. Activating LC-NE neurons disrupted the sleep quality similar to stress, while inhibiting them after stress improved sleep partially through their projections to the preoptic area, a crucial sleep center. Our study reveals that LC-NE neurons and their interactions with hypothalamic sleep neurons orchestrate the sleep microarchitecture and play a crucial role in mediating the negative impact of stress on sleep.\nView lab website: https:\/\/chunglab.med.upenn.edu\/","start_date":"2023-01-10 12:00:00","end_date":"2023-01-10 13:00:00","_links":{"self":[{"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/events\/25926"}],"collection":[{"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/events"}],"about":[{"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/types\/tribe_events"}],"author":[{"embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/users\/26507"}],"replies":[{"embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/comments?post=25926"}],"version-history":[{"count":9,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/events\/25926\/revisions"}],"predecessor-version":[{"id":25963,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/events\/25926\/revisions\/25963"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/media\/25961"}],"wp:attachment":[{"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/media?parent=25926"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/tags?post=25926"},{"taxonomy":"tribe_events_cat","embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/tribe_events_cat?post=25926"},{"taxonomy":"wsuwp_university_location","embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/wsuwp_university_location?post=25926"},{"taxonomy":"wsuwp_university_org","embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/wsuwp_university_org?post=25926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}