{"id":31871,"date":"2024-09-25T12:51:19","date_gmt":"2024-09-25T19:51:19","guid":{"rendered":"https:\/\/medicine.wsu.edu\/news\/?post_type=tribe_events&p=31871"},"modified":"2024-10-02T09:48:22","modified_gmt":"2024-10-02T16:48:22","slug":"tmp-seminar-oct8","status":"publish","type":"tribe_events","link":"https:\/\/medicine.wsu.edu\/news\/event\/tmp-seminar-oct8\/","title":{"rendered":"Translational Medicine and Physiology Seminar Series"},"content":{"rendered":"

By Washington State University \u2013 Department of Translational Medicine and Physiology<\/p>\n

Caspase-Mediated Regulation of Stress Responses<\/h2>\n

October 8, 2024
\n12:10\u20131:00 P.M. PDT
\nSAC 347 or via Zoom<\/a>
\nMeeting ID: 998 2122 0897
\nPasscode: 901049<\/h3>\n

Chronic stress and inflammation are major risk factors for disease. Heightened stress responses suggest a failure to sense resolution of the stressor. Recently, we found that proteolytic cleavage of limited amounts of fatty acid synthase (FASN) releases a stable C-terminal fragment (FASN-CTF) that promotes an anti-inflammatory program including gene expression, metabolic programs and lipid droplets. Our current findings resolve how caspase is differentially regulated in stress responses versus cell death.<\/p>\n

Speaker: Benjamin Weaver, PhD
\n<\/strong>Assistant Professor, UT Southwestern Medical Center<\/p>\n

Benjamin (Ben) Weaver is an Assistant Professor in the Department of Pharmacology. He also holds appointments in the Department of Physiology, the Hamon Center for Regenerative Science and Medicine, and the Harold C. Simmons Comprehensive Cancer Center. In 2018, Ben established the Weaver lab as an Endowed Scholar where he holds the title of Virginia Murchison Linthicum Scholar in Medical Research. His group studies gene-environment interactions with particular interest in how the outcomes of these interactions impact development, stress responses, aging, stemness and innate immunity. The Weaver lab combines cross-disciplinary approaches using genetics, proteomics, metabolomics and biochemical analyses along with diverse models including C. elegans, mammalian cell culture, and in vitro systems.<\/p>\n

\n

For more information contact\u00a0Michelle Sanchez<\/a>.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Chronic stress and inflammation are major risk factors for disease. Join us as Benjamin Weaver, PhD, an assistant professor at UT Southwestern Medical Center, presents: Caspase-Mediated Regulation of Stress Responses.<\/p>\n","protected":false},"author":34189,"featured_media":31872,"comment_status":"open","ping_status":"closed","template":"","meta":{"_wsuwp_accessibility_report":[],"_tribe_events_status":"","_tribe_events_status_reason":""},"tags":[],"tribe_events_cat":[69,66],"wsuwp_university_location":[],"wsuwp_university_org":[],"event_city":"Spokane","event_state":"WA","event_venue":"SAC 347","event_organizer":"","event_organizer_email":"","event_organizer_phone":"","event_organizer_website":"","event_website":"https:\/\/wsu.zoom.us\/j\/99821220897?pwd=s0aR59Q53EFPe4n0XOH1IuxU76brdr.1&from=addon","event_cost":"","event_excerpt":"By Washington State University \u2013 Department of Translational Medicine and Physiology\nCaspase-Mediated Regulation of Stress Responses\nOctober 8, 2024\n12:10\u20131:00 P.M. PDT\nSAC 347 or via Zoom\nMeeting ID: 998 2122 0897\nPasscode: 901049\nChronic stress and inflammation are major risk factors for disease. Heightened stress responses suggest a failure to sense resolution of the stressor. Recently, we found that proteolytic cleavage of limited amounts of fatty acid synthase (FASN) releases a stable C-terminal fragment (FASN-CTF) that promotes an anti-inflammatory program including gene expression, metabolic programs and lipid droplets. Our current findings resolve how caspase is differentially regulated in stress responses versus cell death.\nSpeaker: Benjamin Weaver, PhD\nAssistant Professor, UT Southwestern Medical Center\nBenjamin (Ben) Weaver is an Assistant Professor in the Department of Pharmacology. He also holds appointments in the Department of Physiology, the Hamon Center for Regenerative Science and Medicine, and the Harold C. Simmons Comprehensive Cancer Center. In 2018, Ben established the Weaver lab as an Endowed Scholar where he holds the title of Virginia Murchison Linthicum Scholar in Medical Research. His group studies gene-environment interactions with particular interest in how the outcomes of these interactions impact development, stress responses, aging, stemness and innate immunity. The Weaver lab combines cross-disciplinary approaches using genetics, proteomics, metabolomics and biochemical analyses along with diverse models including C. elegans, mammalian cell culture, and in vitro systems.\n\nFor more information contact\u00a0Michelle Sanchez.","start_date":"2024-10-08 12:10:00","end_date":"2024-10-08 13:00:00","_links":{"self":[{"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/events\/31871"}],"collection":[{"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/events"}],"about":[{"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/types\/tribe_events"}],"author":[{"embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/users\/34189"}],"replies":[{"embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/comments?post=31871"}],"version-history":[{"count":3,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/events\/31871\/revisions"}],"predecessor-version":[{"id":31951,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/events\/31871\/revisions\/31951"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/media\/31872"}],"wp:attachment":[{"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/media?parent=31871"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/tags?post=31871"},{"taxonomy":"tribe_events_cat","embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/tribe_events_cat?post=31871"},{"taxonomy":"wsuwp_university_location","embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/wsuwp_university_location?post=31871"},{"taxonomy":"wsuwp_university_org","embeddable":true,"href":"https:\/\/medicine.wsu.edu\/news\/wp-json\/wp\/v2\/wsuwp_university_org?post=31871"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}