CHRISTOPHER HAYWORTH, PhD
PhD, University of Texas
BS, University of Montana
Postdoctoral, University of Texas at Austin
Postdoctoral, University of Pennsylvania
Dr. Christopher Hayworth has a broad synapse-to-systems training in neurobiology. Most of his work involves one and two photon repeated intracranial brain imaging studies using AAV-directed expression of transgenes that allow for optical monitoring of intracellular calcium and the manipulation of intracellular regulatory pathways. In addition to these cell-specific manipulations, he has expanded into the sleep field using polysomnography, EEG/EMG, to record and monitor phases of sleep including rapid eye movement, REM, non-REM and wakefulness. He enjoys getting on the river, playing guitar, painting and reading science fiction.
Hayworth CR, Moody SE, Chodosh LA, Krieg P, Rimer M, Thompson WJ. Induction of neuregulin signaling in mouse schwann cells in vivo mimics responses to denervation. J Neurosci. 2006 Jun 21;26(25):6873-84. PubMed PMID: 16793894.
Hayworth CR, Rojas JC, Gonzalez-Lima F. Transgenic mice expressing cyan fluorescent protein as a reporter strain to detect the effects of rotenone toxicity on retinal ganglion cells. J Toxicol Environ Health A. 2008;71(24):1582-92. doi: 10.1080/15287390802414190. PubMed PMID: 18850458
Hayworth CR, Gonzalez-Lima F. Pre-symptomatic detection of chronic motor deficits and genotype prediction in congenic B6.SOD1(G93A) ALS mouse model. Neuroscience. 2009 Dec 15;164(3):975-85. doi: 10.1016/j.neuroscience.2009.08.031. Epub 2009 Aug 20. PubMed PMID: 19699279; PubMed Central PMCID: PMC2783710
Hayworth CR, Rojas JC, Padilla E, Holmes GM, Sheridan EC, Gonzalez-Lima F. In vivo low-level light therapy increases cytochrome oxidase in skeletal muscle. Photochem Photobiol. 2010 May-Jun;86(3):673-80. doi: 10.1111/j.1751-1097.2010.00732.x. Epub 2010 Apr 16. PubMed PMID: 20408982
Ingiosi A, Hayworth CR, Harvey D, Singletary K, Rempe M, Wisor J, Frank M. A role for astroglial calcium in mammalian sleep and sleep regulation. Curr Biol. 2020 Sep 18; S0960-9822(20)31242. PubMed PMID: 32976809