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Elson S. Floyd College of Medicine

Faculty and Staff Directory

Crystal Lederhos Smith, PhD

Assistant Professor
Department of Community and Behavioral Health

Dr. Smith currently holds the position of Assistant Research Professor at the Washington State University Elson S. Floyd College of Medicine. She is experienced in advanced quantitative analytics and multiple forms of qualitative analysis. Broadly, her research addresses Substance Use. Her research focuses on cannabis, opioids, pain, and genomics. This has led to collaborations locally, within the Spokane and Coeur d’Alene communities, as well as nation- and worldwide. She has been a Co-Investigator or Research Supervisor on over $15 million in grants and contracts over the 8 years she has been with WSU, resulting in over 30 peer reviewed publications and a 2 book chapters. She has reviewed for 18 journals and currently serves on the Society for Prevention Research International Committee; the Center for Cannabis Policy, Research, and Outreach Board; and she a member of the Center for Novel Therapeutics in Addiction Psychiatry.


  • PhD, Prevention Science, Washington State University, Spokane WA
  • MS, Family and Consumer Science (Summa Cum Laude), University of Idaho, Coeur d’Alene, ID
  • BS, Psychology (Summa Cum Laude), Gonzaga University, Spokane, WA


  • Elson S. Floyd College of Medicine Excellence in Teaching award, 2020
  • Winning team member, Society for Prevention Research Sloboda and Burkoski Cup – 2018
  • ICPSR Summer Program in Quantitative Methods of Social Research “The Population Assessment of Tobacco and Health (PATH) Study Data User Workshop: Biomarker Restricted-Use Files” Competitive workshop attendee – 2018
  • CPDD Travel Award for Early Career Investigators – 2018
  • Washington State University Excellence Award – 2017
  • Gamma Sigma Delta Honor Society, 2011, University of Idaho

Previous Academic and Clinical Positions

Adjunct Faculty
Gonzaga University – Spokane, Washington

Clinical Research Supervisor
Washington State University – Spokane, Washington

Mental Health Specialist & Research Educator
Kootenai Behavioral Health – Youth Acute Unit, Coeur d’Alene, Idaho

Psychosocial Rehabilitation Specialist & Service Coordinator
Mental Wellness Clinic of Coeur d’ Alene, Coeur d’ Alene, Idaho

Research Educator
Kootenai Health, Coeur d’Alene, Idaho

Selected Publications:


Smith CL, Cooper BR, Miguel A, Hill L, Roll J, McPherson S. Predictors of cannabis and tobacco co-use in youth: exploring the mediating role of age at first use in the population assessment of tobacco health (PATH) study. J Cannabis Res. 2021 Jun 1;3(1):16. doi: 10.1186/s42238-021-00072-2. PubMed PMID: 34074338; PubMed Central PMCID: PMC8170934.

Smith, C.L., Waters, S., Spellacy, D., Burduli, E., Brooks, O., Carty, C., Ranjo, S., McPherson, S., Barbosa-Leiker, C. (2021). Substance use in pregnant women during the COVID-19 pandemic. Journal of Reproductive and Infant Psychology, 1-14.

Miguel, A.Q.C., Smith, C.L., Burduli, E., Roll, J., McPherson, S. (2021). Long-term functioning to provide empirical support for the clinical relevance of treatment outcomes for methamphetamine use disorders. Journal of Substance Abuse Treatment, 124, 108291.

Barbosa-Leiker, C., Smith, C.L., Crespi, E., Brooks, O., Burduli, E., Carty, C., Hebert, L., Waters, S., Ranjo, S.* & Gartstein, M. (2021). Stress, coping, and resources needed during the COVID-19 pandemic in a sample of perinatal women. BMC Pregnancy and Childbirth, 21(1), 1-13.

Smith, C.L., Jenkins, G., Burduli, E., Tham, P., Miguel, A., Roll, J., McPherson, S. (2020). Crossover Associations of Alcohol and Smoking, Craving and Biochemically Verified Alcohol and Nicotine Use in Heavy Drinking Smokers. Behavioral Pharmacology, 31(7), 702-705 DOI:  10.1097/FBP.0000000000000568.

Barbosa-Leiker, C., Burduli, E., Smith, C.L., Brooks, O., Orr, M., & Gartstein, M. (2020).  Daily Cannabis Use During Pregnancy and Postpartum in a State with Legalized Recreational Cannabis. Journal of Addiction Medicine, 14(6), 467. DOI: 10.1097/ADM.0000000000000625.

Dyck, D.G., Weeks, D.L., Smith, C.L., Shaw, M. (2020). Multiple Family Group Intervention for Spinal Cord Injury: Quantitative and Qualitative Comparison with Standard Education. Journal of Spinal Cord Medicine, 1-11. DOI:  10.1080/10790268.2019.1710946.

Burduli, E., Smith, C.L., Tham, P., Shogan, M., Johnson, R.K., McPherson, S. (2019). Development and Application of a Primer and Reference Assessment Tool for Neonatal Abstinence Syndrome: A Phase I Pilot Study. Contemporary Clinical Trials Communications, 17. DOI: 10.1016/j.conctc.2019.100494.

Smith, C.L., Vandermause, R., Severtsen, B., Barbosa-Leiker, C., Wilson, M., Roll, J. (2018) Seeking chronic pain relief: A hermeneutic exploration. Pain Management Nursing, 19(6), 652-662. DOI:  10.1016/j.pmn.2018.05.001

McPherson, S.M., Smith, C.L., Dobscha, S., Morasco, B., Demidenko, M., Meath, T., Lovejoy, T.I. (2018) Changes in pain intensity following discontinuation of long-term opioid therapy for chronic non-cancer pain. Pain, 159(10), 2097. DOI: 10.1097/j.pain.0000000000001315.

McPherson, S., Burduli, E., Smith, C.L., Herron, J., Oluwoye, O., Hirchak, K., Orr, M.F., McDonell, M., & Roll, J. (2018). A review of contingency management for the treatment of substance use disorders: Adaptation for underserved populations, use of experimental technologies, and personalized optimization strategies. Substance Abuse and Rehabilitation, 9, 43. DOI: 10.2147/SAR.S138439.

McPherson, S. M., Burduli, E., Smith, C.L., Brooks, O. Orr, M.F., Barbosa-Leiker, C., Hoesktra, T., McDonell, M., Murphy, S., Layton, M.  Roll, J. (2018). Predictors of tobacco and alcohol co-use from ages 15 to 32: The Amsterdam Growth and Health Longitudinal Study. Experimental and Clinical Psychopharmacology. DOI: 10.1037/pha0000203.

Orr, M.F., Smith, C.L., Finlay, M., Martin, S.C., Brooks, O., Oluwoye, O., Leickly, E., McDonell, M., Burduli, E., Barbosa-Leiker, C., Layton, M., Roll, J. M., McPherson, S.M. (2018). Pilot investigation: Randomized controlled analog trial for alcohol and tobacco smoking co-Addiction using contingency management. Behavioural Pharmacology, 29(5), 462. DOI:  10.1097/FBP.0000000000000379. PMCID: PMC6035091.

Smith, C.L., Skaer, T.L., Orr, M., Barbosa-Leiker, C. Howell, D.N., Dyck, D.G. (2017) Development of Multi-family Group and Mindfulness treatment for chronic pain: Preliminary outcomes. Musculoskeletal Disorders and Treatment, 3(4). DOI: 10.23937/2572-3243.1510042.

McPherson, S., Brooks, O., Barbosa-Leiker, C., Lederhos, C., Lamp, A., Murphy, S., Layton, M., & Roll, J. (2016). Examining longitudinal stimulant use and treatment attendance as parallel outcomes in two contingency management randomized clinical trials. Journal of Substance Abuse Treatment, 61, 18-25. DOI: 10.1016/j.jsat.2015.08.008. Full text

Shaw, M.R., Lederhos, C., Howell, D., Haberman, M., Fleming, S. & Roll, J. (2016) Nurses’ perceptions of caring for childbearing women who misuse opioids. The American Journal of Maternal/Child Nursing, 41(1), 37-42. DOI: 10.1097/NMC.0000000000000208.